A Review of On the Psychobiological Differences among Tetrahydrocannabinol, Cannabinol, Cannabidiol and Cannabigerol

The endocannabinoid system plays a physiological natural anti-inflammatory anticancer role and the pharmacological effects of cannabinoids from Cannabis plant simply reflect action endogenous ones. Therefore, therapeutic point view cannot be understood without taking into consideration physio-pathological system. Despite great number potentially molecules with plant, they may synthetized within four archetypic molecules, which consist tetra-hydro-cannabinol (THC), cannabinol (CBN), cannabigerol (CBG) cannabidiol (CBD). All play similar activity, whereas their psychological are different. THC is only psychotropic sychedelic cannabinoid, other three have no effect, but exert an important anxiolytic activity. Moreover, acts as direct enzyme responsible for annabinoid degradation, by enhancing cannabinoid content. Unfortunately, despite experimental studies, clinical use in treatment systemic human diseases still at beginning.